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- W2360101265 abstract "Objective To analyze the value of cardiac troponin I(CTn I)and electrocardiography measurement in predicting TA-induced cardiotoxicity in patients with breast cancer.Methods This study was conducted among 137 breast cancer patients,to investigate the heart rhythm,the voltage of R wave,the change of ST-T by 15-lead ECGs and serum CTnI concentrations and the left ventricular ejection fraction(LVEF)before and after each cycle of the chemotherapy.Results The serum CTnI concentrations of patients were(0.014±0.012)ng/L and no abnormal ECGs before the chemotherapy.After the first period of chemotherapy,the second course and the third course,the serum CTnI concentrations of patients increased to(0.034±0.013)ng/L、(0.121±0.046)ng/L、(0.238±0.128)ng/L and the number of patients with a LVEF reduction by over 10% were 36、54 and 71 separately.Furthermore,the incidence of abnormal ECGs were 82.5%、55.47% and 40.0%.Conclusion CTnI and electrocardiography can be a useful marker for early prediction of TA-induced cardiotoxicity in patients with breast cancer." @default.
- W2360101265 created "2016-06-24" @default.
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- W2360101265 date "2011-01-01" @default.
- W2360101265 modified "2023-09-24" @default.
- W2360101265 title "Value of Cardiac TroponinI and Electrocardiography Measurement in Prediction of TA-induced Cardiotoxicity in Breast Cancer Patients" @default.
- W2360101265 hasPublicationYear "2011" @default.
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