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- W2360126024 abstract "Preeclampsia is a common pathological obstetrics disease and a major cause of maternal and perinatal morbidity and mortality.The etiology of pathological obstetrics disease is not very clear to us.Most scholars believe that it relates to the factors of vas-cular endothelial cell injury caused by Oxidative stress,placental shallow implantation,and destruction of immune balance,endothelial cell dysfunction caused by endothelial cell injury is hot issue of etiology research,CD40 ligand(CD40L;CD154) and its receptor CD40,costimulatory molecules of the tumor necrosis factor(TNF) and TNF receptor family.Interaction can promote endothelial cell and smooth muscle cell expression and release cytokines,tissue factor,adhesion molecules and metalloproteinases,these substances directly or indirectly involved in modulating immune responses and inflammation,resulting in endothelial cell damage,and CD40/CD40L in-volved in occurrence and development of Atherosclerosis,CD40/CD40L is considered as one possible etiology of preeclampsia because it can induce inflammation response and immunity dysfunction,which brings new ideas and direction to the diagnosis and treatment of preeclampsia.This article is aimed to review the relationship between cd40/cd40l signal system and preeclampsia." @default.
- W2360126024 created "2016-06-24" @default.
- W2360126024 creator A5017744165 @default.
- W2360126024 date "2013-01-01" @default.
- W2360126024 modified "2023-09-25" @default.
- W2360126024 title "The Relationship between CD40/CD40L Signal System and Preeclampsia" @default.
- W2360126024 hasPublicationYear "2013" @default.
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