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- W2360147803 abstract "Objective:To evaluate the hypothesis that gastrin might function as a local growth factor in colorectal neoplasms.Methods:Blood samples were taken from 40 cases colorectal cancer 、10 cases adenomatous polyposis and 40 healthy controls.Tumors and normal tissue were obtained from 40 patients undergoing surgery for colorectal cancer.Gastrin in blood samples and tissue was measured by radioimmunoassay.Results:Plasma gastrin levels were no higher in subjects with colorectal cancer or adenomas than those of controls,but there was significant correlation between plasma gastrin levels and liver metastasis.Besides,there was significant difference among colorectal cancers,adenomatous polyposis and controls.In colorectal cancer subjects,there were no significant correlation between tissue gastrin and Dukes staging,liver metastasis.Conclusion:The results indicat that gastrin may play a stimulating role in the growth of tumor and serve an important indicator of prognosis of colorectal cancer." @default.
- W2360147803 created "2016-06-24" @default.
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- W2360147803 date "1999-01-01" @default.
- W2360147803 modified "2023-09-25" @default.
- W2360147803 title "The Detection of Plasma and Tissue Gastrin in Colorectal Neoplasms" @default.
- W2360147803 hasPublicationYear "1999" @default.
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