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- W2360152259 abstract "Objective Recent studies have suggested that inflammatory factors were the intermediate in the pathogenesy of type 2 diabetes mellitus(T2DM).Our research is to investigate the changes of serum hypersensitive C-reactive protein(HsCRP) and cytokine levels in the very elderly with T2MD.Methods The serum levels of HsCRP,IL-2,IL-6,TNF-αwere observed in 45 very elderly patients with T2MD,and compared with those in 36 very elderly controls.Carotid artery intima-media thickness(IMT) and atherosclerotic plaque were also examined in order to evaluate the degree of atherosclerosis(AS).Results The serum levels of HsCRP,IL-6 and TNF-αwere higher,the serum IL-2 level was lower,and the degree of AS was severer in the very elderly patients with T2MD than those in the very elderly controls.Conclusion The increased levels of HsCRP,IL-6,TNF-α and the decrease level of the IL-2,may participate in the pathogenesis of the very elderly with T2MD,and may have relevance to the development and the severity of AS in these patients." @default.
- W2360152259 created "2016-06-24" @default.
- W2360152259 creator A5033733048 @default.
- W2360152259 date "2010-01-01" @default.
- W2360152259 modified "2023-09-27" @default.
- W2360152259 title "Clinical significance of determination of serum high sensitive C-reactive protein and cytokine levels in the very elderly with type 2 diabetes mellitus" @default.
- W2360152259 hasPublicationYear "2010" @default.
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