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- W2360159611 abstract "Objective: To investigate platelet function with special regard to the role of platelet Pselectin in patients with atrial fibrillation and the clinical significance.Methods: Using flow cytometry technique,the expression of platelet P-selectin and platelet membrane glycoproteinⅡb/Ⅲa(GPⅡb/Ⅲa) receptor in 28 patients with atrial fibrillation(Af) and 21 patients with sinus rhythm(SR) were measured;In addition,mean platelet volum(MPV) and platelet counts(PLT) were measured by automatic hematologic analyzer.Results: Comparing with the normal SR group,the levels of the expression of platelet P-selectin[(11.34±3.02)% vs(8.42±2.13)%] and MPV[(12.77±3.25)fl vs(10.95±2.02)fl] in Af patients were significantly higher(P0.05),and there was an increased trend of platelet GPⅡb/Ⅲa in Af patients,but without statistical significance[(8.56±4.10)% vs(7.17±4.96)%](P0.05).There was no significant difference in PLT between the two groups(P0.05).Conclusions: Evidence of P-selectin increase shows in Af patients and indicates platelet activation,which may correlate to prothrombin state in Af patients." @default.
- W2360159611 created "2016-06-24" @default.
- W2360159611 creator A5020499056 @default.
- W2360159611 date "2005-01-01" @default.
- W2360159611 modified "2023-09-23" @default.
- W2360159611 title "Expression of Platelet P-selectin in Patients with Atrial Fibrillation" @default.
- W2360159611 hasPublicationYear "2005" @default.
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