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- W2360196485 abstract "Aim: The objective of this article is to evaluate the changes of brain hemodynamics and to study the relationship of the changes between hemodynamics and compliance following traumatic brain injury (TBI) using transcranial doppler (TCD). Methods: The model of moderate and severe brain injury was made in cats. The blood velocity of middle cerebral artery (MCA) was measured with TCD after TBI. Pulsatile index (PI), resistance index (RI) and systolic peak/diastonic nadir (S/D) were calculated from TCD findings. Meanwhile, intracranial pressure (ICP), volume pressure reaction (VPR) and pressure volume index (PVI) were measured and calculated using ICP monitor. Results: The blood velocity of MCA became fast gradually after TBI, The peak value occurred at 6 hours after TBI, and tended to be lower after 6 hours and was even lower than that of pretrauma after 24 hours. The values of PI, RI and S/D increased gradually after TBI and were obviously higher than those of pretrauma after 24 hours ( P 0.05). The more severely the brain injured, the more obviously these values changed. ICP and VPR increased and PVI decreased after TBI. There was a positive linear correlation between ICP and systolic velocity , median velocity, PI, S/D ( P 0.01),and between PVI and Vs, diastolic velocity (Vd), Vm, PI ( P 0.01), but there was a negative relationship between VPR and these values above metioned. Conclusion: It is believed that TCD is useful in detecting the changes of hemodynamics after TBI and deducing the changes of ICP and compliance therewith." @default.
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- W2360196485 date "1996-01-01" @default.
- W2360196485 modified "2023-09-22" @default.
- W2360196485 title "Transcranial Doppler for Comparative Studies on Relationship between Brain Hemodynamics and Compliance Following Brain Injuries" @default.
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