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- W2360230746 abstract "Objective To investigate the value of tissue Doppler ultrasound elastography(TDUE)in the diagnosis of breast solid lesions.Methods TDUE was used to examine 46 cases with 54 breast solid lesions(39 benign lesions and 15 malignant lesions).The pathological confirmations were performed after surgical resection.After a size of 1cm2 region of interest(ROI) was placed in the subcutaneous adipose tissue and target lesion,the corresponding type of tissue Doppler and strain curve was achieved.Maximal absolute relaxed strain(max-ARS) of adipose tissues,benign lesions and malignant lesions were also recorded.Results The elastography was performed 3 times for each solid lesion and adipose tissue adjacent to the lesion.Totally 162 curves of adipose tissues,117 curves of benign lesions,and 45 curves of malignant lesions in ROI were acquired with elastographic modality.Two categories of curve,positive wave and negative wave,were achieved.There were all positive waves and no negative waves in 162 curves of adipose tissues.Numbers of positive and negative waves in 117 curves of breast benign lesions were 108 and 9,respectively.Numbers of positive and negative waves in 45 curves of breast malignant lesions were 12 and 33,respectively.The categories of curves among the adipose tissues,benign lesions and malignant lesions had statistically significant difference(corrected size of test, χ2=172.37,P0.0001).The difference was significant for the types of curves between adipose tissues and benign lesions(Fisher exact test,P=0.0003)and between adipose tissues and malignant lesions(Fisher exact test,P0.0001).The types of curves between malignant lesions and benign lesions were also considered statistically significant(χ2=72.92,P0.0001).The mean max-ARS of adipose tissues,benign and malignant lesions was(15.57±8.91)%,(6.78±4.48)% and(1.14±2.71)%,respectively,and the difference among them was significant(F=104.21,P0.05).The mean max-ARS of adipose tissues was significantly greater than that of benign lesions and malignant lesions(q=1.32 and 1.85,all P0.05).The mean max-ARS of benign lesions was also statistically larger than that of malignant lesions(q=0.67,P0.05).Conclusions The majority of breast malignant lesions demonstrate negative wave in tissue doppler and strain curve.The max-ARS of benign lesions is greater than that of malignant lesions.Elasticity based on tissue Doppler and strain curve provide evidence for the differentiation of breast benign and malignant lesions." @default.
- W2360230746 created "2016-06-24" @default.
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- W2360230746 date "2012-01-01" @default.
- W2360230746 modified "2023-09-23" @default.
- W2360230746 title "Tissue Doppler and strain curve of tissue Doppler ultrasound elatography of breast solid lesions" @default.
- W2360230746 hasPublicationYear "2012" @default.
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