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- W2360284218 abstract "ObjectiveTo investigate the expression of survivin and phoshatase and tension homology-deleted-on-chromosome FEN (PTEN) gene protein in cholangiocarcinomas and its clinical significance.MethodsThe expression of survivin and PTEN in the cholangiocarcinomatous tissue of 43 cases was respectively investigated by immunohistochemical technique.The relationship between expression of survivin,PTEN and the clinicopathological factors of cholangiocarcinoma was analyzed.ResultsThe positive expression rate of survivin and PTEN in cholangiocarcinoma was 58% (25/43) and 40% (17/43) respectively.The higher expression of survivin and the lower expression of PTEN were positively related with the TNM phase,differentiation degree and metastasis of cholangiocarcinoma (P0.05).ConclusionExpression of tumor suppressor,survivin and PTEN gene,could be helpful in predicting the biological behavior and prognosis of cholangiocarcinoma." @default.
- W2360284218 created "2016-06-24" @default.
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- W2360284218 date "2005-01-01" @default.
- W2360284218 modified "2023-09-25" @default.
- W2360284218 title "Expression of survivin and PTEN in cholangiocarcinoma and its clinical implication" @default.
- W2360284218 hasPublicationYear "2005" @default.
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