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- W2360308510 abstract "Objective To understand the influence of gastroesophageal reflux disease (GERP) on quality of living (QOL),and evaluate therapeutic effect as well as influence on QOL and cost of two kinds of triple therapy. Methods The patients with GERP from six municipal hospitals of Lishui which have been diagnosed by gastroscope were studied. General condition, symptom, QOL before and after treat and cost in the dlisease were acquired by questionaire. The patients were given PPI combined with motive drug and mucosa-protected drug (scheme A) and H2RAs combined with motive drug and mucosa-protected drug ( scheme B) for 8 weeks respectively. The table of QOL and cost were recorded. The relationship between therapeutic effects, the changes of QOL and the cost were studied. Results (1)112 cases of patients with GERD were collected, the ratio of male to female was 2.4 to 1 , average ages were 47 .9±13.8, the clinical references of two groups were comparable ( P 0 .05) . (2) The total efficacy of scheme A and B was 92 .98 % and 80 % respectively, and A was superior lo B.(3)QOL were influened seriously by GERD, the QOL of high quality decreased from 63.7% to 13.7% in patients with GERD, and that could be restored to 84 % and 63 % through scheme A and B respectively . There were no significant difference in cost between the two schemes.(4)There were significant correlation between therapeutic effects and improvement of QOL. Conclusions The effect of triple therapy to GERD is obvious, and can improve the QOL significantly.The effects of Lansoprazole combined with motive drug and mucosa-protected drug are more significant. This therapy is economical, high efficient and can improve QOL effectively, so it deserves to be spreaded." @default.
- W2360308510 created "2016-06-24" @default.
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- W2360308510 date "2003-01-01" @default.
- W2360308510 modified "2023-09-25" @default.
- W2360308510 title "Evaluation of different therapy on gastroesophageal reflux disease" @default.
- W2360308510 hasPublicationYear "2003" @default.
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