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- W2360331803 abstract "Objective To discuss the safety of using hypotonic contrast agents in population with acute myocardial infarction(AMI) at low or moderate risk for contrast-induced nephropathy(CIN) who underwent urgent percutaneous coronary intervention(PCI).Methods In the CCU room of our hospital,226 patients with AMI received the urgent PCI.According to Mehran contrast-induced nephropathy risk stratification tool,all patients were divided into low or moderate risk group(risk score≤10) and high risk group(risk score10).The isosmotic nonionic contrast agent Iodixanol(subgroup A) and hypotonic contrast agent Iohexol(subgroup B) were randomly used in the low or moderate risk group.Patients with high risk of CIN received Iodixanol.The serum creatinine and blood urea nitrogen levels(baselin e and 24 h,48 h,72 h) were tested.The follow-up was 3 years,and the effects of contrast agents on the renal functions were evaluated.Results There were 3 patients(4.2%) suffered with CIN in subgroup A and 2 patients(2.7%) in subgroup B respectively.No statistical difference was found between the two groups.CIN incidence was 3.5%(5/144) in low or moderate risk group and 9.8%(8/82) in high-risk group,which total CIN incidence was 5.8% lower than it in the literature.Conclusion The appropriate contrast media selected by the risk stratification can effectively reduce the incidence of the CIN in the patients who underwent urgent PCI.The selective using of hypotonic contrast agents(Iohexol) in the low or moderate risk group was safe." @default.
- W2360331803 created "2016-06-24" @default.
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- W2360331803 date "2011-01-01" @default.
- W2360331803 modified "2023-09-25" @default.
- W2360331803 title "Safety of Hypotonic Contrast Agent in Urgent Percutaneous Coronary Interventions" @default.
- W2360331803 hasPublicationYear "2011" @default.
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