FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2360382005> ?p ?o ?g. }

• W2360382005 endingPage "9555" @default.
• W2360382005 startingPage "9551" @default.
• W2360382005 abstract "The quest for ligands that specifically bind to particular G-quadruplex nucleic acid structures is particularly important to conceive molecules with specific effects on gene expression or telomere maintenance, or conceive structure-specific molecular probes. Using electrospray mass spectrometry in native conditions, we reveal a highly cooperative and selective 2:1 binding of CuII-tolylterpyridine complexes to human telomeric G-quadruplexes. Circular dichroism and comparisons of affinities for different sequences reveal a marked preference for antiparallel structures with diagonal loops and/or wide-medium–narrow-medium groove-width order. The cooperativity is attributed to conformational changes in the polymorphic telomeric G-quadruplex sequences, which convert preferably into an antiparallel three-quartet topology upon binding of two ligands." @default.
• W2360382005 created "2016-06-24" @default.
• W2360382005 creator A5010580813 @default.
• W2360382005 creator A5013458899 @default.
• W2360382005 creator A5074031482 @default.
• W2360382005 date "2016-06-03" @default.
• W2360382005 modified "2023-09-30" @default.
• W2360382005 title "Selective and Cooperative Ligand Binding to Antiparallel Human Telomeric DNA G-Quadruplexes" @default.
• W2360382005 cites W1489967197 @default.
• W2360382005 cites W1972600622 @default.
• W2360382005 cites W1975890865 @default.
• W2360382005 cites W1981888951 @default.
• W2360382005 cites W1990635146 @default.
• W2360382005 cites W1991754576 @default.
• W2360382005 cites W1993991835 @default.
• W2360382005 cites W1997427887 @default.
• W2360382005 cites W1997795846 @default.
• W2360382005 cites W2004833536 @default.
• W2360382005 cites W2028345897 @default.
• W2360382005 cites W2028386646 @default.
• W2360382005 cites W2031928292 @default.
• W2360382005 cites W2032698727 @default.
• W2360382005 cites W2033735656 @default.
• W2360382005 cites W2037144426 @default.
• W2360382005 cites W2038138229 @default.
• W2360382005 cites W2039272200 @default.
• W2360382005 cites W2053166926 @default.
• W2360382005 cites W2053234014 @default.
• W2360382005 cites W2056321432 @default.
• W2360382005 cites W2057954591 @default.
• W2360382005 cites W2066414581 @default.
• W2360382005 cites W2089598395 @default.
• W2360382005 cites W2089619525 @default.
• W2360382005 cites W2095195375 @default.
• W2360382005 cites W2120168398 @default.
• W2360382005 cites W2122504832 @default.
• W2360382005 cites W2127213026 @default.
• W2360382005 cites W2132840917 @default.
• W2360382005 cites W2144409714 @default.
• W2360382005 cites W2152055606 @default.
• W2360382005 cites W2153207180 @default.
• W2360382005 cites W2169069102 @default.
• W2360382005 cites W2170925896 @default.
• W2360382005 cites W2320936920 @default.
• W2360382005 doi "https://doi.org/10.1002/chem.201601937" @default.
• W2360382005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27168452" @default.
• W2360382005 hasPublicationYear "2016" @default.
• W2360382005 type Work @default.
• W2360382005 sameAs 2360382005 @default.
• W2360382005 citedByCount "25" @default.
• W2360382005 countsByYear W23603820052017 @default.
• W2360382005 countsByYear W23603820052018 @default.
• W2360382005 countsByYear W23603820052020 @default.
• W2360382005 countsByYear W23603820052021 @default.
• W2360382005 countsByYear W23603820052022 @default.
• W2360382005 countsByYear W23603820052023 @default.
• W2360382005 crossrefType "journal-article" @default.
• W2360382005 hasAuthorship W2360382005A5010580813 @default.
• W2360382005 hasAuthorship W2360382005A5013458899 @default.
• W2360382005 hasAuthorship W2360382005A5074031482 @default.
• W2360382005 hasBestOaLocation W23603820052 @default.
• W2360382005 hasConcept C115260700 @default.
• W2360382005 hasConcept C121332964 @default.
• W2360382005 hasConcept C12554922 @default.
• W2360382005 hasConcept C133571119 @default.
• W2360382005 hasConcept C142089489 @default.
• W2360382005 hasConcept C166014724 @default.
• W2360382005 hasConcept C177336024 @default.
• W2360382005 hasConcept C185592680 @default.
• W2360382005 hasConcept C24107716 @default.
• W2360382005 hasConcept C2780283098 @default.
• W2360382005 hasConcept C552990157 @default.
• W2360382005 hasConcept C55493867 @default.
• W2360382005 hasConcept C62520636 @default.
• W2360382005 hasConcept C71240020 @default.
• W2360382005 hasConcept C8010536 @default.
• W2360382005 hasConcept C83762044 @default.
• W2360382005 hasConcept C86803240 @default.
• W2360382005 hasConceptScore W2360382005C115260700 @default.
• W2360382005 hasConceptScore W2360382005C121332964 @default.
• W2360382005 hasConceptScore W2360382005C12554922 @default.
• W2360382005 hasConceptScore W2360382005C133571119 @default.
• W2360382005 hasConceptScore W2360382005C142089489 @default.
• W2360382005 hasConceptScore W2360382005C166014724 @default.
• W2360382005 hasConceptScore W2360382005C177336024 @default.
• W2360382005 hasConceptScore W2360382005C185592680 @default.
• W2360382005 hasConceptScore W2360382005C24107716 @default.
• W2360382005 hasConceptScore W2360382005C2780283098 @default.
• W2360382005 hasConceptScore W2360382005C552990157 @default.
• W2360382005 hasConceptScore W2360382005C55493867 @default.
• W2360382005 hasConceptScore W2360382005C62520636 @default.
• W2360382005 hasConceptScore W2360382005C71240020 @default.
• W2360382005 hasConceptScore W2360382005C8010536 @default.
• W2360382005 hasConceptScore W2360382005C83762044 @default.
• W2360382005 hasConceptScore W2360382005C86803240 @default.
• W2360382005 hasFunder F4320320893 @default.
• W2360382005 hasFunder F4320325796 @default.
• W2360382005 hasIssue "28" @default.

• next