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- W2360419309 abstract "Objective To investigate the histological changes of the skin with melasma and keratin 10 (CK10) expression. Methods The excess skin in the lateral canthus was acquired after eyelid plasty operation for melasma patients,the paraffin sections was stained with HE,Fontana -Masson and CK10 immunohistochemical staining to observe the pathological changes of the melasma skin and the distribution of CK10. Results The epidermis was thin in the melasma skin. And the melanin can be seen clearly around the basal layer cells.It could be seen in the upper basal layer,the upper hair follicle and dermis. Dermal collagen was disorder,fracture,the number of skin appendages was less than the normal skin. CK10 mainly distributed in the upper stratum of basal epidermis and the most outer layer of sebaceous glands. Conclusion The content of melanin increases in melasma skin,and skin aging features appear in the histological structure. CK10 expresses strongly in the upper stratum of basal epidermis which maybe relate with the excessive differentiation of epidermal cells and the skin aging." @default.
- W2360419309 created "2016-06-24" @default.
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- W2360419309 date "2010-01-01" @default.
- W2360419309 modified "2023-09-25" @default.
- W2360419309 title "Histological features of melasma lesions and the expression of keratin 10" @default.
- W2360419309 hasPublicationYear "2010" @default.
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