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- W2360428196 abstract "Objective To study the significance of P16 gene and the relationship between P16 protein expression and CT findings in peripheral pulmonary carcinoma (PPC).Materials and Methods CT scan was performed in 57 patients with pathologically proved PPC, and the P16 protein expression level of the tumor specimens was estimated with immunohistochemical SABC method.Results P16 protein positive expression rate of PPC specimens was 50.9%, which was significantly lower than that of the adjacent normal lung tissues (P0.01), and P16 protein expression level bore a parallel relationship to cell differentiation grade of PPC (P0.01). P16 protein expression rate was extremely low (P0.01) when PPC demonstrated the following features on CT scans: the diameter of tumor over 3cm, deeply lobulated, spinous process, vanishing of adjacent extrapleural fat line, and mediastinal lymph node enlargement.Conclusion The results indicate that the deletion of P16 protein expression in PPC is linked to the carcinogenesis, progression, differentiation and CT signs." @default.
- W2360428196 created "2016-06-24" @default.
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- W2360428196 date "2000-01-01" @default.
- W2360428196 modified "2023-09-24" @default.
- W2360428196 title "Correlation Study of P16 Protein Expression and CT Features in Peripheral Pulmonary Carcinoma" @default.
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