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- W2360475158 abstract "Objective To study the telomerase activity in human renal cell carcinoma and to evaluate its correlation with the clinicobiologic features of the neogrowth. Methods The telomerase activity was studied by means of a polymerase chain reaction based telomerase activity assay (TRAP) in 32 renal cell carcinoma tissues,32 normal renal tissues and 32 paracancer tissues and its correlation with the clinicopathologic features of the tumor was evaluated. Results Telomerase activity was strongly positive in 17 renal cell carcinoma tissues,positive in 12 and negative in 3,the total positive rate being 91%.In 32 samples of normal renal cortex tissues only 2 was weakly positive (6%) and it was positive in 6 paracancer tissues (19%).The difference was conspicuous (P0.01). Conclusions The positive rate of telomerase activity was significantly higher in renal cell carcinoma tissues and might serve as a prognostic marker for estimating the biologic characteristics of renal cell carcinoma." @default.
- W2360475158 created "2016-06-24" @default.
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- W2360475158 date "1999-01-01" @default.
- W2360475158 modified "2023-09-24" @default.
- W2360475158 title "Telomerase activity in renal cell carcinoma" @default.
- W2360475158 hasPublicationYear "1999" @default.
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