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- W2360481091 abstract "Objective To explore the effect of folic acid on plasma level of HCY,SOD,MDA and blood lipid in hyperhomocysteinemia.(Methods)Hyperhomocysteinemia model by high methionine diet was developed,30 male rats(average weight 150±50 g)were randomly divided into three groups: normal control group,no treatment group;methionine group and folic acid intervention group.Blood was drawn from heart after feeding for 6 weeks.The plasma level of HCY,SOD,MDA and blood lipid were measured in every group.(Results) HCY and MDA significantly increased and SOD significantly decreased in Met group and Met+Fa group when compared with control group(P0.01).When Met+Fa group was compared with Met group,HCY and MDA obviously decreased and SOD increased(P0.05).However,TC,TG and HDL had no significant difference among Met group,Met+Fa group and control group(P0.05).Conclusion Hyperhomocysteinemia could enhance lipid peroxidation and folic acid could attenuate this effect of hyperhomocysteinemia and thus,prevent injury of blood vessel." @default.
- W2360481091 created "2016-06-24" @default.
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- W2360481091 date "2006-01-01" @default.
- W2360481091 modified "2023-09-28" @default.
- W2360481091 title "Effect of Folic Acid on Hyperhomocysteinemia Induced by Methionine in Rat" @default.
- W2360481091 hasPublicationYear "2006" @default.
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