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- W2360486539 abstract "Objective To investigate the immunomodulatory activity of Astragalus decoction and Astragalus polysaccharide in mice infected with Cryptosporidium..Methods Immunosuppression was induced by initially feeding the mice with b-methasone acetate for 8 days.At Day-9, the mice were immunized by oral feeding with 1×106 Cryptosporidium oocysts. The infected mice were then treated with Astragalus decoction and its polysaccharide for 10 days.Fecal oocysts were daily counted.Intestinal histopathology,T cell subsets and serum IL-2,IL-4 and IFN-gamma levels were examined.Mice in the control group were treated with conventionally used Western medicines..Results Compared with the control group,mice receiving Western medicines,Astragalus decoction and its polysaccharide group had a lower number of fecal oocysts,less intestinal histopathological changes,and a higher level of CD4,CD4 8,IL-2,IL-4 and IFN-gamma. Conclusion Astragalus decoction and its polysaccharide may promote the immune function of mice infected with Cryptosporidium." @default.
- W2360486539 created "2016-06-24" @default.
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- W2360486539 date "2011-01-01" @default.
- W2360486539 modified "2023-09-26" @default.
- W2360486539 title "Immunomodulatory effect of astragalus and its polysaccharide on the Cryptosporidium-infected mice" @default.
- W2360486539 hasPublicationYear "2011" @default.
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