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- W2360493006 abstract "ObjectiveTo investigate p38 MAPK protein expression in human breast tumors and the regulation of preoperative chemotherapy. MethodsWe assessed p38 MAPK protein in 50 cases of breast cancer and adjacent normal tissue and that of breast benign tumors in 14 cases by Western blot. 15 cancer patients received preoperative CAF or TA protocol. Results The p38 protein level in tumors was significantly greater than that in the normal tissues, while there was not significant difference between benign tumors and corresponding normal tissue. p38 protein T/N ratio was higher in patients with lymph node metastasis than patients without( P 0 01). p38 MAPK protein level in the 15 cancer patients who received preoperative chemotherapy did not decrease significantly. Conclusionp38 may play an important role in the occurrence and metastasis of human breast cancer." @default.
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- W2360493006 date "2002-01-01" @default.
- W2360493006 modified "2023-09-26" @default.
- W2360493006 title "Overexpression of p38 MAPK protein in breast cancer and the regulation of preoperative chemotherapy" @default.
- W2360493006 hasPublicationYear "2002" @default.
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