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- W2360509075 abstract "Objectives To investigate the relationship between Chlamydia pneumoniae(CP) infection,inflammation and coronary atherosclerosis, and to evaluate their potential roles in restenosis.Methods Five hundred and fifty five subjects were divided into coronary artery atherosclerosis patients and non-coronary artery atherosclerosis controls according to coronary angiography. Their baseline characteristics were carefully recorded. The serum CRP and CP-specific antibody IgA were measured by ELISA.Of the subjects,89 patients who had stent implantation were followed up for six months. Quantitative coronary angiography was used to assess the rate of lumen loss. Results Positive rate and titer of CP IgA in patients with coronary atherosclerosis were higher than those in control group .Serum CRP level was also higher in coronary atherosclerotic group than in control group, and increased with increasing extent of the lesions. There was no significant difference in rate of neointima proliferation after stent placement between the seropositive group and seronegative group.But CRP increased in patients with neointima proliferation.Conclusions Previous infection with CP was associated with coronary artery atherosclerosis, but it could not predict the restenosis after stent placement. However, serum CRP played an important role in the process of both atherosclerosis and restenosis." @default.
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- W2360509075 date "2004-01-01" @default.
- W2360509075 modified "2023-09-26" @default.
- W2360509075 title "Potential roles of Chlamydia pneumoniae infection in coronary atherosclerosis and restenosis in old patients" @default.
- W2360509075 hasPublicationYear "2004" @default.
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