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- W2360517271 abstract "OBJECTIVE To study the protective effects of Tianzhenzi capsule ( TZZ) on focal cerebral ischemia reperfusion injure in rats. METHODS The rat model of middle cerebral artery ischemia 2 h/reperfusion 22 h was observed. The neurological scale, cerebral infracted volume,cerebral water content,the activities of nitricoxide synthase ( NOS) ,superoxide dismutase ( SOD) and the content of malonaldehyde ( MDA) in brain were measured. RESULTS The neurological scale,cerebral infracted volume,cerebral water content,activity of NOS and content of MDA were significantly declined by TZZ. Meanwhile,activity of SOD was significantly higher than model group. CONCLUSION TZZ may facilitate the protection against cerebral ischemia/ reperfusion damage. Action mechanisms might be relevant to reduced lipoperoxidation injury in brain cells through inhibiting the activities of the NOS,increasing the avtivities of the SOD." @default.
- W2360517271 created "2016-06-24" @default.
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- W2360517271 date "2009-01-01" @default.
- W2360517271 modified "2023-09-22" @default.
- W2360517271 title "Protective effect of Tianzhenzi capsule on focal cerebral ischemia-reperfusion injure in rats" @default.
- W2360517271 hasPublicationYear "2009" @default.
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