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- W2360629670 abstract "Objective To evaluate the clinical effect of domestic oxaliplain(Ai Heng),mitomycin C(MMC) and 5 fluorouracil(5 Fu) in treating metastatic cancer of the colon and rectum and to observe toxic side effects of thse drugs.Methods Ai Heng(L OHP) 130mg/m 2 ivgtt, at Day 1;MMC 6mg/m 2 iv,at Day 1;CF 150mg/m 2 ivgtt,from Day 1 to Day 5;5 Fu 500mg iv,5 Fu 500mg ivgtt from Day 1 to Day 5.Each cycle included 21 days,after two continuous cycles,evaluation was performed.Results Among 19 patients,overall respond rate was 63.2%(12/19),thereinto,complete respond rate(CR) was 21.1%(4/19),partial respond rate(PR) was 42.1%(8/19).Main toxic side effects were leukopenia,the frequency of which was 42.1% anemia and thrombocytopenia,the frequency was 21.1% and 26.4% respectively.42.1% of patients appeared neural toxicity.These sympotoms would disappear gradually after ceasing the treatment.Conclusion Efficiency of the regiment(LMF/CF)which mainly contains Ai Heng is perfect in treating metastasis cancer of the colon and rectum,and the toxic side effect of the regimen is little." @default.
- W2360629670 created "2016-06-24" @default.
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- W2360629670 date "2001-01-01" @default.
- W2360629670 modified "2023-09-23" @default.
- W2360629670 title "Clinical observation of domestic oxaliplain mitomycin C and 5-fluorouracil in treating metastatic cancer of the colon and rectum" @default.
- W2360629670 hasPublicationYear "2001" @default.
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