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- W2360647464 abstract "The phosphoinositide 3-kinase( PI3K) protein family member can generate phosphoinositide lipids by the activation of growth factors. The lipid products of PI3K act as second messengers to bind and activate diverse cellular target proteins. These events form a complex signaling cascade,which ultimately plays a critical role in many cellular activities such as proliferation,differentiation,chemotaxis,survival,trafficking and glucose homeostasis. This review introduces the classification and structural features of PI3K family members in detail. Then,the PI3K-dependent signaling pathway and its related functions are presented." @default.
- W2360647464 created "2016-06-24" @default.
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- W2360647464 date "2013-01-01" @default.
- W2360647464 modified "2023-09-23" @default.
- W2360647464 title "Research Progress on Structure and Function of PI3K" @default.
- W2360647464 hasPublicationYear "2013" @default.
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