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- W2360675897 abstract "AIM:To investigate the role of p38 MAPK signaling pathway in the receptor-mediated endocytosis.METHODS:The effects of p38 MAPK on the receptor-mediated endocytosis were observed by using Alexa 594-conjugated Transferrin,in the presence of p38 specific inhibitor SB203580 or ERK pathway specific inhibitor PD98059,or using p38 knockout techniques.RESULTS:In the process of receptor-mediated endocytosis,p38 was activated by phosphorylation.Furthermore,the receptor-mediated endocytosis was inhibited by pretreatment with SB203580 or p38 knockout,while pretreatment with PD98059 had no effect on this process.CONCLUSION:p38 MAPK signaling pathway plays a role in the regulation of receptor-mediated endocytosis." @default.
- W2360675897 created "2016-06-24" @default.
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- W2360675897 date "2007-01-01" @default.
- W2360675897 modified "2023-09-24" @default.
- W2360675897 title "p38 MAPK signaling pathway is involved in the regulation of receptor-mediated endocytosis" @default.
- W2360675897 hasPublicationYear "2007" @default.
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