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- W2360684822 abstract "Objective: To study the influence of EGF (epidermal growth factor) on synthesis of testosterone in rat Leydig cells. Methods: After excision of submaxillary gland, changes of enzymes and metabolite related to testosterone synthesis in Leydig cells were studied through enzyme histochemistry and image analysis. Results: 3 weeks after excision of submaxillary gland,3β hydroxysteroid dehydrogenase (3β HSD), non specific esterase (NSE), succinate dehydrogenase (SDH) activities and amount of lipid in Leydig cells were not changed significantly. However, lactate dehydrogenase (LDH) activity was decreased significantly. 5 weeks after the operation,the activities of 3β HSD,NSE, SDH and LDH were decreased significantly, and amount of lipid was increased . 7 weeks after the operation,the changes of enzymes and lipid were similar to those in the 5 th week, and the activities of four enzymes were still at the low level. Conclusion: The deficiency of endogenous EGF may lead to the decline of testosterone synthesis in rat Leydig cells. (J Beijing Med Univ, 2000,32:167 169)" @default.
- W2360684822 created "2016-06-24" @default.
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- W2360684822 date "2000-01-01" @default.
- W2360684822 modified "2023-09-25" @default.
- W2360684822 title "Histochemistry observation of rat Leydig cells after excision of submaxillary gland" @default.
- W2360684822 hasPublicationYear "2000" @default.
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