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- W2360701556 abstract "Objective:Based on isolation culture and drug sensitivity test of Gram-negative Enterbacteriaceae,to understand the drug-resistance rate difference between adults and children,so as to guide the rational use of antibacterial agents in clinic.Methods: Gram-negative Enterbacteriaceae were isolated from specimens of children and adult patients from January 2009 to June 2011,bacterial identification was performed by VITEK-32 automatic microbiological analyzer,and drug sensitivity test was done with Kirby-Bauer method,then the drug-resistance rates of isolates from children and adults to antimicrobial agents were compared.Results: The Gram-negative Enterbacteriaceae were found 479 strains in children and 1056 strains in adults,Escherichia coli,Klebsiella pneumoniae and Enterobacter cloacae ranked the top three.The ESBLs of Escherichia coli and Klebsiella pneumoniae had higher positive rate in specimens of children than those in adults(P0.05).The AmpC positive rate of Enterobacter cloacae had significant difference between children and adults(P0.05).The Escherichia coli,Klebsiella pneumoniae and Enterobacter cloacae from specimens of children and adults exhibited various resistance to different antibiotics,with obvious difference(P0.05).Conclusion: The main Gram-negative Enterbacteriaceae isolates showed diverse drug resistance to the same antibacterial agents,so rational antibacterial agents use should be in line with the drug sensitivity test in clinical anti-infection treatment." @default.
- W2360701556 created "2016-06-24" @default.
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- W2360701556 date "2013-01-01" @default.
- W2360701556 modified "2023-09-23" @default.
- W2360701556 title "Comparison of Gram-negative Enterobacteriaceae drug-resistance rate between children and adults" @default.
- W2360701556 hasPublicationYear "2013" @default.
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