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- W2360704423 abstract "Objective To analyze the characteristics of a patient with hypopituitarism and reviewed related literatures to investigate the pathogenesis of hypopituitarism induced by syringomyelia associated with Chiari malformation.Methods Detailed physical examination was performed in a male whose complaint was retardation of growth.Then the serum gonadal hormones,thyroid hormones and adrenal cortical hormones level were assayed.The GnRH stimulating test,X-ray of wrist joint and pituitary MRI were also performed.Results Patients has a history of perinatal injury.The body height is 143cm and no secondary sexual characters were developed.The LH,T,TSH,FT3 and 24-hous uretic free cortisol is 0.00mIU/L,0.10ng/ml,1.23mIU/L,3.47pmol/L and 46.0nmol/L respectively.The GnRH stimulating test shows that the peak of LH which appeared at 120-min is 0.29mIU/L.The bone age is 13 and the MRI of pituitary shows: the shape is abnormal,the image of stalk is dimness,and cerebellar tonsil hereniation.Conclusions Chiari malformation is the basis of the hypopituitarism induced by syringomyelia.Perinatal injury is an inducement.Hypopituitarism happened along the development of syringomyelia.So patients with syringomyelia,especially syringomyelia associated with Chiari malformation should be examined the pituitery function." @default.
- W2360704423 created "2016-06-24" @default.
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- W2360704423 date "2011-01-01" @default.
- W2360704423 modified "2023-09-24" @default.
- W2360704423 title "Hypopituitarism induced by syringomyelia associated with Chiari malformation and review of literatures" @default.
- W2360704423 hasPublicationYear "2011" @default.
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