Matches in SemOpenAlex for { <https://semopenalex.org/work/W2360710950> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2360710950 abstract "Objective To study the relationship between rs4680 polymorphism of catechol-O-methyl transferase gene( COMT) and the cognitive function of patients with schizophrenia. Methods Schizophrenia was diagnosed in 167 patients in Mental Hospital of Jining from July 2008 to June 2010 according to the diagnostic and statistical manual of mental disorders versionⅣ( DSM-Ⅳ) diagnostic criteria. For the control group,98 normal volunteers were chosen. Wisconsin card sorting test( WCST) was used to evaluate the cognitive function,all the cases were given module card reasoning classification test of different color,shape,number,and accomplishment were recorded. Polymerase chain reaction( PCR) and restriction fragment length polymorphism( RFLP) techniques were performed for COMT rs4680 polymorphism. The chi-square test and analysis of variance was used for statistical analysis. Results When the schizophrenia group( 167 cases) and the normal control group( 98 cases) were compared,no difference was seen on the COMT genotype or the allele frequencies( χ2= 4. 40,P = 0. 110; χ2= 0. 726,P = 0. 394). There were differences of continuity error number on different genotype group of schizophrenia patients( F = 11. 496,P 0. 01). G / G group was higher than G / A group( 56. 20 ± 15. 11 and 43. 44 ± 15. 35 respectively,P 0. 05). There was no difference in other items of WCST on different genotype group of schizophrenia patients( F = 0. 125,F = 0. 535,F =0. 178,F = 1. 861,F = 0. 102,F = 1. 305,P 0. 05). Conclusions There is no association between the rs4680 polymorphism of COMT gene and schizophrenia. However,there might be association between rs4680polymorphism and some cognitive function. The cognitive impairment of G / G genotype is serious." @default.
- W2360710950 created "2016-06-24" @default.
- W2360710950 creator A5042505557 @default.
- W2360710950 date "2012-01-01" @default.
- W2360710950 modified "2023-09-25" @default.
- W2360710950 title "Association study of rs4680 polymorphism of catechol-o-methyl transferase gene and the cognitive function of patients with schizophrenia" @default.
- W2360710950 hasPublicationYear "2012" @default.
- W2360710950 type Work @default.
- W2360710950 sameAs 2360710950 @default.
- W2360710950 citedByCount "0" @default.
- W2360710950 crossrefType "journal-article" @default.
- W2360710950 hasAuthorship W2360710950A5042505557 @default.
- W2360710950 hasConcept C104317684 @default.
- W2360710950 hasConcept C118552586 @default.
- W2360710950 hasConcept C126322002 @default.
- W2360710950 hasConcept C135763542 @default.
- W2360710950 hasConcept C14216870 @default.
- W2360710950 hasConcept C149737253 @default.
- W2360710950 hasConcept C15744967 @default.
- W2360710950 hasConcept C168007829 @default.
- W2360710950 hasConcept C169900460 @default.
- W2360710950 hasConcept C185361966 @default.
- W2360710950 hasConcept C2776412080 @default.
- W2360710950 hasConcept C2778420670 @default.
- W2360710950 hasConcept C2778524067 @default.
- W2360710950 hasConcept C54355233 @default.
- W2360710950 hasConcept C71924100 @default.
- W2360710950 hasConcept C86803240 @default.
- W2360710950 hasConcept C90924648 @default.
- W2360710950 hasConceptScore W2360710950C104317684 @default.
- W2360710950 hasConceptScore W2360710950C118552586 @default.
- W2360710950 hasConceptScore W2360710950C126322002 @default.
- W2360710950 hasConceptScore W2360710950C135763542 @default.
- W2360710950 hasConceptScore W2360710950C14216870 @default.
- W2360710950 hasConceptScore W2360710950C149737253 @default.
- W2360710950 hasConceptScore W2360710950C15744967 @default.
- W2360710950 hasConceptScore W2360710950C168007829 @default.
- W2360710950 hasConceptScore W2360710950C169900460 @default.
- W2360710950 hasConceptScore W2360710950C185361966 @default.
- W2360710950 hasConceptScore W2360710950C2776412080 @default.
- W2360710950 hasConceptScore W2360710950C2778420670 @default.
- W2360710950 hasConceptScore W2360710950C2778524067 @default.
- W2360710950 hasConceptScore W2360710950C54355233 @default.
- W2360710950 hasConceptScore W2360710950C71924100 @default.
- W2360710950 hasConceptScore W2360710950C86803240 @default.
- W2360710950 hasConceptScore W2360710950C90924648 @default.
- W2360710950 hasLocation W23607109501 @default.
- W2360710950 hasOpenAccess W2360710950 @default.
- W2360710950 hasPrimaryLocation W23607109501 @default.
- W2360710950 hasRelatedWork W1481286756 @default.
- W2360710950 hasRelatedWork W1980642296 @default.
- W2360710950 hasRelatedWork W2136716532 @default.
- W2360710950 hasRelatedWork W2360026999 @default.
- W2360710950 hasRelatedWork W2360219662 @default.
- W2360710950 hasRelatedWork W2362541267 @default.
- W2360710950 hasRelatedWork W2380493939 @default.
- W2360710950 hasRelatedWork W2381063784 @default.
- W2360710950 hasRelatedWork W2387075373 @default.
- W2360710950 hasRelatedWork W2390983764 @default.
- W2360710950 hasRelatedWork W2392111561 @default.
- W2360710950 hasRelatedWork W2392900685 @default.
- W2360710950 hasRelatedWork W2994747566 @default.
- W2360710950 hasRelatedWork W3029330697 @default.
- W2360710950 hasRelatedWork W3029810370 @default.
- W2360710950 hasRelatedWork W3030742530 @default.
- W2360710950 hasRelatedWork W3031031735 @default.
- W2360710950 hasRelatedWork W3032032473 @default.
- W2360710950 hasRelatedWork W3032539388 @default.
- W2360710950 hasRelatedWork W2779437418 @default.
- W2360710950 isParatext "false" @default.
- W2360710950 isRetracted "false" @default.
- W2360710950 magId "2360710950" @default.
- W2360710950 workType "article" @default.