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- W2360741098 abstract "Objective:To compare the expression of regulatory molecules and apoptosis of lymphocytes in peripheral blood of mothers in third trimester of pregnancy and cord blood of neonates,explore the immunologic difference between mothers and neonates.Methods:The apoptosis rates of of lymphocytes in peripheral blood(PBLs) of mothers in third trimester of pregnancy and cord blood(CBLs)of neonates from 20 women in third trimester of pregnancy and 20 normal pregnant women were detected by flow cytometry(FCM).The expression of apoptosis regulatory molecules(Fas,FasL,Bcl-2) on PBLs and CBLs were detected by immunohistochemical stainning.Results:The apoptosis rate of lymphocytes in CBLs was significantly higher than that in PBLs in the normal pregnant women and women in third trimester of pregnancy(P0.05).The expression levels of Fas and FasL in CBLs were lower than those in PBLs(P0.05).There was no difference in the expression of Bcl-2 between 2 groups.The expression levels of Fas and BcL-2 in CBLs were significantly lower than those in PBLs in women in third trimester of pregnancy(P0.05),but there was no difference in the expression of FasL between 2 groups.Conclusion:The apoptosis rates and expression levels of regulatory molecules of lymphocytes in peripheral blood of mothers in third trimester of pregnancy and cord blood of neonates had significant difference,which may play an important role in maintaining the balance of immune tolerance and immune rejection." @default.
- W2360741098 created "2016-06-24" @default.
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- W2360741098 date "2009-01-01" @default.
- W2360741098 modified "2023-09-25" @default.
- W2360741098 title "Analysis on apoptosis of lymphocytes in peripheral blood of mothers in third trimester of pregnancy and cord blood of neonates." @default.
- W2360741098 hasPublicationYear "2009" @default.
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