Matches in SemOpenAlex for { <https://semopenalex.org/work/W2360782817> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2360782817 abstract "Objective To investigate the possible role of VPA therapy in the change of the plasma leptin level and insulin level of epileptic patients and development of the wight gain,also the machanism of leptin resistance and insulin resistance.Methods The weight and fasting insulin levels and leptin levels in 33 epileptic patients treated with VPA alone at last 3 months and 21 epileptic patients without therapy were determined.The body mass index(BMI)and the plasma leptin level and homeostasis model assessment(HOMA)index in the two groups were compared.Results The HOMA index in the VPA therapy group was 1.7049±0.6525,higher than that of the controls(0.8230±0.2635,P0.05).The plasma leptin level and the body mass index(BMI)in the VPA therapy group were 8.8503±4.7924μg/ml and 23.7202±2.5182,also higher than that of the controls(2.8490±1.3962μg/ml and 20.8468±1.6815,P0.05).The plasma insulin level in the VPA therapy group was 7.3406±2.7921MU/L higher than that of the controls 4.1033±1.0466MU/L.Conclusion VPA therapy for period of three monthes leads to hyperinsulinemia and hyperleptinemia.It may be one of the mechanisms of development of insulin resistance and leptin resistance." @default.
- W2360782817 created "2016-06-24" @default.
- W2360782817 creator A5061494181 @default.
- W2360782817 date "2006-01-01" @default.
- W2360782817 modified "2023-09-23" @default.
- W2360782817 title "The impact of sodium valproate therapy on the levels of plasma leptin and insulin in epileptic patients" @default.
- W2360782817 hasPublicationYear "2006" @default.
- W2360782817 type Work @default.
- W2360782817 sameAs 2360782817 @default.
- W2360782817 citedByCount "0" @default.
- W2360782817 crossrefType "journal-article" @default.
- W2360782817 hasAuthorship W2360782817A5061494181 @default.
- W2360782817 hasConcept C118552586 @default.
- W2360782817 hasConcept C126322002 @default.
- W2360782817 hasConcept C134018914 @default.
- W2360782817 hasConcept C2777391703 @default.
- W2360782817 hasConcept C2778186239 @default.
- W2360782817 hasConcept C2779306644 @default.
- W2360782817 hasConcept C2780221984 @default.
- W2360782817 hasConcept C2780613262 @default.
- W2360782817 hasConcept C2780988686 @default.
- W2360782817 hasConcept C511355011 @default.
- W2360782817 hasConcept C71924100 @default.
- W2360782817 hasConceptScore W2360782817C118552586 @default.
- W2360782817 hasConceptScore W2360782817C126322002 @default.
- W2360782817 hasConceptScore W2360782817C134018914 @default.
- W2360782817 hasConceptScore W2360782817C2777391703 @default.
- W2360782817 hasConceptScore W2360782817C2778186239 @default.
- W2360782817 hasConceptScore W2360782817C2779306644 @default.
- W2360782817 hasConceptScore W2360782817C2780221984 @default.
- W2360782817 hasConceptScore W2360782817C2780613262 @default.
- W2360782817 hasConceptScore W2360782817C2780988686 @default.
- W2360782817 hasConceptScore W2360782817C511355011 @default.
- W2360782817 hasConceptScore W2360782817C71924100 @default.
- W2360782817 hasLocation W23607828171 @default.
- W2360782817 hasOpenAccess W2360782817 @default.
- W2360782817 hasPrimaryLocation W23607828171 @default.
- W2360782817 hasRelatedWork W11547947 @default.
- W2360782817 hasRelatedWork W2013102015 @default.
- W2360782817 hasRelatedWork W2013330362 @default.
- W2360782817 hasRelatedWork W2032717475 @default.
- W2360782817 hasRelatedWork W2056595390 @default.
- W2360782817 hasRelatedWork W2080436138 @default.
- W2360782817 hasRelatedWork W2105388223 @default.
- W2360782817 hasRelatedWork W2112682655 @default.
- W2360782817 hasRelatedWork W2353291364 @default.
- W2360782817 hasRelatedWork W2354493388 @default.
- W2360782817 hasRelatedWork W2356383454 @default.
- W2360782817 hasRelatedWork W2363380455 @default.
- W2360782817 hasRelatedWork W2365812783 @default.
- W2360782817 hasRelatedWork W2370808530 @default.
- W2360782817 hasRelatedWork W2401641818 @default.
- W2360782817 hasRelatedWork W2743654529 @default.
- W2360782817 hasRelatedWork W2798079695 @default.
- W2360782817 hasRelatedWork W2950119296 @default.
- W2360782817 hasRelatedWork W2977674062 @default.
- W2360782817 hasRelatedWork W3134681487 @default.
- W2360782817 isParatext "false" @default.
- W2360782817 isRetracted "false" @default.
- W2360782817 magId "2360782817" @default.
- W2360782817 workType "article" @default.