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- W2360896166 abstract "OBJECTIVE:To study the protective effects and mechanism of Radix Adenophorae Potanini Korsh Polysaccharides(RAPS) on carbon tetrachloride(CCl4)-induced primary cultured hepatocytes injury in rats.METHODS:The rat hepatocytes were separated by perfusion in situ.RAPS was added to the cultured medium after incubating the rat hepatocytes for 36 hours,meanwhile,CCl4 was added to induce hepatocytes injury.The levels of ALT,AST,SOD,GSH-PX,and MDA after cultivation for 24h and 48h were determined respectively.And the survival rate of hepatocytes was determined at 48h by MTT method.RESULTS:RAPS could inhibit the CCl4-induced enhanced activities of ALT and AST,inhibit MDA production and the decreasing of SOD and GSH-PX induced by hepatocytes injury,and significantly improve the survival rate of hepatocytes.CONCLUSION:RAPS could effectively protect the primary cultured rat hepatocytes against CCl4 induced injury,which is possibly associated to its anti-oxidative activity." @default.
- W2360896166 created "2016-06-24" @default.
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- W2360896166 date "2007-01-01" @default.
- W2360896166 modified "2023-09-22" @default.
- W2360896166 title "Protective Effects of Radix Adenophorae Potanini Korsh Polysaccharides on Carbon Tetrachloride-induced Injury of Primary Cultured Hepatocytes in Rats" @default.
- W2360896166 hasPublicationYear "2007" @default.
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