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- W2360933923 abstract "Objective:To study the expressions of heparanse and S-100 protein in gastric carcinoma of human.Methods:The tis- sues of gastric carcinoma in 40 cases were divided into early stage group and late stage group according to the pathology typing.The can- cer cells had metastasized in lymphoid nodes in late stage group,but not in early stage group.The ultramicrostructure and the expressions of heparanse and S-100 protein in gastric carcinoma were detected with light,electron microscope,hybridization in situ and immunohis- tochemical methods.Results:The number density and area density of heparanse positive cells in late stage of gastric carcinoma were sig- nificantly higher than those in early stage (P0.01),but S-100 protein positive cells in early stage were higher than that in late stage (P0. 01).Under TEM,there were more lymphocytes and dendritic cells in early stage and fewer tumor cells that penetrated basal membrane; the dendritic cell processes contacted with lymphocytes,and few basement membranes were destroyed.In late stage,there were fewer dendritic cells and lymphocytes,but more tumor cells that penetrated basal membrane could be observed.Conclusion:The expression levels ofheparanse and S-100 protein were correlated with metastasisand prognosis of gastric carcinoma,and can be regarded as markers that judge the invasion,metastasis and prognosis of the gastric carcinoma." @default.
- W2360933923 created "2016-06-24" @default.
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- W2360933923 date "2008-01-01" @default.
- W2360933923 modified "2023-09-22" @default.
- W2360933923 title "Expressions of Heparanse and S-100 protein in gastric carcinoma of human" @default.
- W2360933923 hasPublicationYear "2008" @default.
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