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- W2360941270 abstract "[Objective] To investigate the effect and safety of lonorxicam on postoperation analgesia to head-cervix malignant tumor. [Methods] 40 patients who administered postoperation analgesia after the operation of head-cervix malignant tumor were divided into 2 groups randomly, Group L and group F, 20 case in each group, 40mg lonorxicam were administered in group L, 1 mg fentanyl in group F, dilute the drug with normal saline to 100 ml respectively. Use Fornia analgesia pump, continuous infusion rate at 2 mL/h, bolus does at 1ml,lockout interval at 15 min. 30min before the finish of the operation, the loading dose 8mg lonorxicam was given in group L; while in group F, the loading dose 0.05 mg fentanyl was given when the operation was finished, Patient-controlled intravenous analgisia started after the operation. The VAS score, the Ramsay score and side effects were recorded at 2, 4, 8, 12, 24, 36 and 48 hours after the operation respectively. [Results] The VAS score in each timepoint in group L was not significantly different from that in group F (P 0.05). The Ramsay scores in postoperative 2, 4 hours were significantly higher in group F than those in group L (P 0.05), and there was no significantly difference between the two groups 8hs after the operation (P 0.05); The side effects in group F were signifcantly higher than that of group L (P 0.05). [Conclusion] The analgesia effect of lonorxicam is similar to that of fentanyl, but lonorxicam is safer, and there is less side effects. Lonorxicam is effective and safe for the postoperation analgesia to head-cervix malignant tumor." @default.
- W2360941270 created "2016-06-24" @default.
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- W2360941270 date "2005-01-01" @default.
- W2360941270 modified "2023-09-23" @default.
- W2360941270 title "Evaluation of lonorxicam for postoperative analgesia in patients receiving operation of head-cervix malignant tumor" @default.
- W2360941270 hasPublicationYear "2005" @default.
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