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- W2360951914 abstract "Objective To explore the evaluation effect of coagulation parameters on the severity and prognosis of the disease in critically ill patients. Methods Information of 309 critically ill patients hospitalized in ICU was selected from November 2010 to June 2012. According to APACHEⅡ score,patients were divided into slight group( APACHEⅡ score 20) and severe group( APACHEⅡscore≥20),which were calculated within 24 hours of admission. According to prognosis 14 days after the date of admission,patients were divided into survival group and death group. The venous blood of all patients within 2 hours of admission were collected and platelet( PLT),platelet pressure product( PCT),large platelet ratio( PLCR),mean platelet volume( MPV),platelet distribution width( PDW),prothrombin time( PT),prothrombin activity degress( PTA),activated partial thromboplastin time( APTT),fibrinogen( FIB),thrombin time( TT),D- dimer( D- Dimer) and serum Ca 2 + concentration were detected. The evaluation effect of coagulation parameters of patients with severe on the severity and prognosis was analyzed by non- parametric tests and logistic regression analysis. Results Compared with the slight group,PLT,PTA,FIB significantly reduced,PT and TT significantly prolonged, D- dimer significantly increased in severe group( P 0. 05); compared with the survival group,serum Ca 2 + concentration significantly reduced,PT,APTT,TT significantly prolonged,PTA significantly reduced and D- dimer significantly increased in death group( P 0. 05); D- dimer entered into the regression model eventually( P 0. 05). Conclusion Coagulation indicators of patients with critically ill had an significant evaluation effect to explore the severity and prognosis. D- dimer could be be considered as a risk factor for death in patients with critically ill." @default.
- W2360951914 created "2016-06-24" @default.
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- W2360951914 date "2013-01-01" @default.
- W2360951914 modified "2023-10-06" @default.
- W2360951914 title "Evaluation Effect of Coagulation Indicators on the Severity and Prognosis of the Disease in Critically Ill Patients" @default.
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