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- W2360954031 abstract "A single nucleotide polymorphism(SNP) at site 248of melanocortin receptor 1gene(MC1R) is known from European horse breeds,in which the homozygous genotype(ee) is related with the chestnut coat color of European horse individuals.To confirm the polymorphism of site 248of MC1Rgene in Chinese horse,three horse breeds of Guizhou pony,Southwest horse and Ili horse were chosen as samples with coat color of three monochromatic(chestnut,black,bay) and three kinds of complex coat color.Two pairs specific primers were designed.Two fragments,124and 481bp,were amplificated by allelespecific polymerase chain reaction(AS-PCR) method.The polymorphism of site 248in MC1Rgene was further approved by cloning and sequencing of the DNA fragments.The results showed that genotypes of all samples with coat color of chestnut were heterozygous genotype(Ee).However,the genotypes of other samples were Ee either,in which the coat colors included bay,black,grey,spotted but not chestnut.It suggested that the SNP at site 248of MC1Rgene might be unrelated with the chestnut coat color in native Chinese horse breeds." @default.
- W2360954031 created "2016-06-24" @default.
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- W2360954031 date "2012-01-01" @default.
- W2360954031 modified "2023-09-25" @default.
- W2360954031 title "Association of Polymorphism in MC1R Gene at Site 248 with Chestnut Coat Color in Three Chinese Horse Breeds" @default.
- W2360954031 hasPublicationYear "2012" @default.
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