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- W2360960557 abstract "Several cryoprotectants were employed to study the protective effect on the freeze-drying process of the oleanolic acid-loaded nanosuspensions (OLA-LS) in order to select the optimum formulation.The protective effect was evaluated by measuring the mean particle size of samples before and after freeze-drying process.Sucrose with the concentration of 10% was selected as the optimum cryoprotectant. The average size of excellent sample was 236.3 nm (versus 211.2 nm of fresh one), and a much higher polydispersity index of 0.242 (versus 0.180).The optimum lyophilized powder could be obtained with suitable type of cryoprotectant with appropriate concentration and proper freeze-drying conditions." @default.
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- W2360960557 date "2007-09-01" @default.
- W2360960557 modified "2023-09-23" @default.
- W2360960557 title "[Freeze-drying of oleanolic acid-loaded nanosuspensions]." @default.
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