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- W2360991857 abstract "Objective To analyze the resting-state brain network related to visuospatial working memory( VSWM) in patients with rTLE. Discussing the functional mechanism underlying the deficit of VSWM. Methods 15 patients with rTLE and 16 controls underwent RS-fMRI scanning,the VSWM related network at rest was extracted utilizing multiple independent component analysis( MICA),comparing the between-group differences of spatial distribution of the cerebral network and that of the functional connectivity within-networks. Results The distribution of the VSWM related resting-state network( RSN) in the rTLE group were virtually consistent with that in controls,involving the dorsolateral prefrontal lobe and parietal lobe in the right hemisphere,inferior parietal lobe and partial posterior lobe of cerebellum within the left hemisphere( Pα 0. 05,alphasim corrected). Between-group differences showed that the rTLE group had a decreased FC within the right superior frontal lobe( BA8 area),right middle frontal lobe and right ventromedial prefrontal lobe,compared with the controls( Pα 0. 05,alphasim corrected). Meanwhile,the regions of increased FC in rTLE localized within the right superior frontal lobe( BA11 area),right superior parietal lobe and left posterior lobe of cerebellum. Conclusion The results suggested the VSWM related RSN in patients with rTLE was altered and it probably implied a functional plasticity to VSWM by increasing the FC within the ipsilateral cerebral network." @default.
- W2360991857 created "2016-06-24" @default.
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- W2360991857 date "2013-01-01" @default.
- W2360991857 modified "2023-09-24" @default.
- W2360991857 title "The cerebral network of visuospatial working memory in patients with rTLE: A resting state fMRI study" @default.
- W2360991857 hasPublicationYear "2013" @default.
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