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- W2360992227 abstract "Objective To investigate the role of IL 4 in the induction of neonatal tolerance. Methods Intrathymic injection of 2.5 ×10 7 Wistar spleen cells in neonatal SD rats was performed followed by mixing lymphocyte culture (MLC) with Wistar rat spleen cells (20?Gy) at 4 6 weeks of age. The levels of IL 4 and IFN γ were measured by ELISA on the third day. Results The level of IL 4 in primed neonatal SD rats was significantly higher ( P 0.001 ) and IFN γ significantly lower ( P 0.001 ) than in control rats. Conclusion The production of IL 4 was critical for the induction of neonatal tolerance." @default.
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- W2360992227 date "2000-01-01" @default.
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- W2360992227 title "The role of IL-4 in the induction of neonatal tolerance" @default.
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