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- W2361062015 abstract "DNA methylation is an epigenetic modification associated with gene transcription regulation, X-chromosome inactivation, regulation of development and cell differentiation. Aberrant DNA methylation has been linked to cancer. The advent of microarray technology has provided new opportunities for high-throughput study on DNA methylation. Various microarray-based methods depend on different pretreatments including immunoprecipitation and restriction digestion. Al-though each technique has its limitations, the immunoprecipitation method has high specificity, and the restriction digestion method shows high sensitivity. Together they provide many choices to the study of genome-wide DNA methylation profile in cancer." @default.
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- W2361062015 date "2008-03-10" @default.
- W2361062015 modified "2023-10-17" @default.
- W2361062015 title "Microarray-based methods to identify DNA methylation in cancer" @default.
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- W2361062015 doi "https://doi.org/10.3724/sp.j.1005.2008.00295" @default.
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