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- W2361097488 abstract "Objective To investigate the feasibility and effectiveness of catheter radiofrequency therapy for patients with focal atrial fibrillation (AF). Methods From May 1998 through November 1999,26 patients with paroxysmal focal AF refractory to antiarrhythmic drug therapy underwent radiofrequency ablation.Bipolar electrogram of high right atrium,His bundle and coronary sinus were recorded simultaneously with surface ECG lead I、aVF、V 1.Left and right superior pulmonary veins were mapped with ablation catheters to determine the origin of atrial premature contractions (PACs).If the origin of PACs were not in the superior pulmonary veins,the left and right inferior pulmonary veins as well as other sites of both atria were mapped subsquently.Once the ablation target was found,radiofrequency current was delivered during AF or the presence of PACs.The end point of ablation was the disappearence of AF or the number of PACs reduced significantly,and AF could not be reinitiated by the initiation protocal successfully used before ablation. Results All 26 patients were followed up for 1 18 months.The origin of most (71 4%) PACs were in the left or right superior pulmonary veins,less commonly at other sites of both atria.Radiofrequency ablation therapy was successful in 12/26 (46 2%),effective in 4/26 (15 4%) and unsuccessful in 8/26 (30 8%) patients respectively.Complications during ablation procedure occurred in 19/26 (73 1%) patients,most of them were minor.There were two major complications including cardiac arrest due to vasovagal reflex in one patient and acute cardiac temponade and cerebral embolism in another.Both patients were alive after energetic treatment,but the hemiplegia of the patient suffered from stroke had not improved. Conclusion The prelimenary results indicate focal AF treated with radiofrequency seems to be feasible and effective.However,this therapeutic technique needs to be improved." @default.
- W2361097488 created "2016-06-24" @default.
- W2361097488 creator A5054066077 @default.
- W2361097488 date "2000-01-01" @default.
- W2361097488 modified "2023-09-28" @default.
- W2361097488 title "Preliminary result of 26 paroxysmal atrial fibrillation patients treated with catheter radiofrequency abiation" @default.
- W2361097488 hasPublicationYear "2000" @default.
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