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- W2361103674 abstract "Objective:To investigate the mechanism of the treatment of Gufusheng for steroid-induced avascular necrosis of the femoral head(SANFH).Methods:Thirty-two rabbits were randomly divided into control group( n =12) and making-model group ( n =20).Prednisone Acetate was injected to the animals in model group.In the 6 th and 8 th week,two rabbits of both groups were killed respectively to observe whether the model was successful.Then the rabbits in the making-model group was divided into Gufusheng group(Group A)and model group(Group B)randomly.The residual of the control group formed group C.Group A was given Gufusheng.The other two groups were all given physiological saline.After four weeks’ treatment,the level of tumor necrosis factor-α(TNF-α)of serum in three groups was examined.Results:The level of TNF-α in making-model group was significantly higher than that of control group(P0 001).But the level of TNF-α in Gufusheng group was significantly less than that of model group(P0 01).Conclusion:The rise of TNF-α may be one of the most important factors in the occurrence of steroid-induced avascular necrosis of femoral head,and Gufusheng can treat steroid-induced avascular necrosis of femoral head by decreasing the level of TNF-α." @default.
- W2361103674 created "2016-06-24" @default.
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- W2361103674 date "2004-01-01" @default.
- W2361103674 modified "2023-09-23" @default.
- W2361103674 title "Effects of Gufusheng on TNF-α of rabbits with steroid-induced avascular necrosis of the femoral head" @default.
- W2361103674 hasPublicationYear "2004" @default.
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