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- W2361116667 abstract "Objective To study the repair role of reduced glutathione(GSH) of different dose on acute liver injury of mice.Methods The experimental acute liver injury model was established by injection of carbon tetrachloride in mice.Different dose GSH was given by peritoneal administration.Seven days later,all the animals were sacrificed.The levels of serum ALT and AST were measured and liver pathology was determined by HE stain.Results The levels of serum ALT and AST increased,and hepatic cell adipose was common in liver injury model group compared with the control group.In GSH groups,the levels of serum ALT and AST were higher,but hepatic cell swelling and adipose degeneration were alleviated compared with those in the liver injury model group.There was no obvious difference between the two GSH groups with different dose GSH in histopathology.Conclusion GSH has a repair effect on the acute liver injury induced by carbon tetrachloride.But extra dose of GSH doesn't provide better repair effect." @default.
- W2361116667 created "2016-06-24" @default.
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- W2361116667 date "2009-01-01" @default.
- W2361116667 modified "2023-09-24" @default.
- W2361116667 title "Repair role of reduced glutathione of different dose on acute liver injury of mice" @default.
- W2361116667 hasPublicationYear "2009" @default.
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