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- W2361122988 abstract "Objective This study was designed to investigate the correlation among NT-proBNP and renal function in elderly patients with hypertension so as to evaluate its role in hypertension health management.Methods Serum prosome brain natriuretic peptide(proBNP)levels were determined and renal function was evaluated by estimated glomerular filtration rate(eGFR) which calculated by cock-croft formula in 285 elderly patients with hypertension,correlations and liner regression were drawn between proBNP values and eGFR.Results proBNP level was significantly elevated in patients with decreased eGFR,especially in those eGFR60 ml/min·1.73m2(P0.05).Correlation analysis also showed that proBNP levels had altered in parallel with changes in eGFR.Negative correlation was observed between proBNP and eGFR with a correlation coefficient of-0.144(P=0.03).Liner regression analysis show that the change of renal function in hypertension will induce the change of serum proBNP level,accompany with the decrease of eGFR,proBNP level increased significantly(β=-0.146,t=-2.244,P=0.026).Conclusions Changes in proBNP levels may reflect parallel changes in renal function in elderly with hypertension,suggesting that proBNP may be utilized as a clinical indicator in hypertension management." @default.
- W2361122988 created "2016-06-24" @default.
- W2361122988 creator A5056353600 @default.
- W2361122988 date "2010-01-01" @default.
- W2361122988 modified "2023-09-23" @default.
- W2361122988 title "Study to evaluate the relationship between NT-proBNP and renal function in elderly hypertension patients" @default.
- W2361122988 hasPublicationYear "2010" @default.
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