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- W2361123025 abstract "Objective To explore value of detecting mutations of K-ras in diagnosis of pancreat- ic cancer.Methods After the samples of peripheral blood were collected from 15 patients with pancre- atic cancer and other 30 without the disease,plasma DNA was extracted.Mutated K-ras was detected with RFLP-PCR and types of the mutations determined with direct sequencing.Results K-ras muta- tions were found in 11 of the 15 patients (73%) with pancreatic cancer but only 2 with chronic pancre- atitis.Pathological examination showed that 1 of the latter 2 patients had atypical ductal hyperplasia. Conclusions Detection of mutations of K-ras in plasma can be used adjuvant diagnosis of pancreatic cancer." @default.
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- W2361123025 date "2001-01-01" @default.
- W2361123025 modified "2023-09-26" @default.
- W2361123025 title "Value of detecting mutations of K-ras in plasma of periperal blood in diagnosis of pancreatic cancer" @default.
- W2361123025 hasPublicationYear "2001" @default.
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