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- W2361145800 abstract "Objective:To prepare the meloxicam gels and evaluate its transdermal delivery.Methods: In vitro diffusion of drug from gel matrix and the permeation tests through excised mouse skin were carried out by two compartment diffusion cells.Results:The permeation rate of meloxicam was effectively enhanced by oleic acid,oleum red sabinae,azone and oleum eucalypti .Oleic acid showed the highest permeation coefficient and the enhancement ratios.Conclusion:The optimum formulation of the gels consisted of 0.1% meloxicam,2% oleic acid and Carborpol/HPMC(2∶1) mixture.The permeation process of meloxicam from the hydrogel formulation could be described by Higuchi equation." @default.
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- W2361145800 date "2002-01-01" @default.
- W2361145800 modified "2023-09-25" @default.
- W2361145800 title "Preparation and evaluation of meloxicam gels for transdermal delivery" @default.
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