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- W2361240514 abstract "Objective To compare the effects of Granisetron plus Dexamethasone and small dose Droperidol with Granisetron alone or placebo in the prevention of reducing post operative nausea and vomiting(PONV) after laparoscopic cholecystectomy.Methods Eighty six ASA Ⅰ Ⅱ female patients scheduled for laparoscopic cholecystectomy were randomly allocated to three groups:Group A(n=32):Dexamethasone 10 mg?Droperidol 1.25 mg were administered I.V. before anesthesia induction and Granisetron 3 mg was administered I.V.at the end of operation;GroupB(n=28):Normal Saline 5 ml was administered I.V.before anesthesia and Granisetron 3 mg was administered I.V. at the endof operation;Group C:Normal Saline 5 ml was administered I.V.before anesthesia and at the end of operation respectively.The occurrence of PONV was assessedduring 24 h after the operation.Result In the first 2h,the incidence of PONV in group A and group B were both significantly lowered than that in group C( p 0.01 and p 0.05 respectively);During the time from 2 12 h after operation,the incidence of PONV in group A was signifi cantly lowered than that in group C,but there is no significant difference of incidence between group B and group C( p 0.05);During the time from 12 24 h after operation,the incidence of PONV in group A was significantly lowered than those in group B and group C( p 0.05 and p 0.01 respectively).Conclusion Granisetron combined with Dexamethasone and a small dose of Droperidol is superior to Granisetron alone and placebo in preventing PONV undergoing laparoscopic cholecystectomy." @default.
- W2361240514 created "2016-06-24" @default.
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- W2361240514 date "2003-01-01" @default.
- W2361240514 modified "2023-09-25" @default.
- W2361240514 title "CLINICAL STUDY OF THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING AFTER LAPAROSECOPIC CHOLECYSTECTOMY" @default.
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