Matches in SemOpenAlex for { <https://semopenalex.org/work/W2361267256> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2361267256 abstract "Objective:To observe the effect of mifepristone on vascular endothelial function in insulinresistance rats induced by high-fat diet.Methods:Fasting blood glucose,fasting insulin,HOMA insulin resistance index and insulin sensitivity index were used to assess whether the insulin-resistance model was successful;serum corticosterone was used to reflect the changes of glucocorticoid in the development of insulin resistance;serum nitric oxide,anti-superoxide vitality units,blood pressure,blood lipids and aorta nitric oxide synthase were used to evaluate the vascular endothelial function.Results:After administered of high-fat diet for eight weeks,rats in model group displayed insulin resistance with high blood glucose,high insulin,abnormal blood lipids,low serum nitric oxide and anti-superoxide,low activity of aorta nitric oxide synthase;mifepristone could significantly improve insulin resistance and lipid metabolism disorders,increase serum nitric oxide(P0.01) and anti-superoxide vitality units(P0.05),improve the activity of endothelial nitric oxide svnthase(P0.05).Conclusion:Insulin resistance is copied successfully and accompanied endothelial dysfunction in SD rats with high-fat diet for eight weeks.Mifepristone can significantly improve insulin resistance and endothelial dysfunction,which may be dute to the biological effects of antagonism of mifepristone to glucocorticoid." @default.
- W2361267256 created "2016-06-24" @default.
- W2361267256 creator A5006157399 @default.
- W2361267256 date "2009-01-01" @default.
- W2361267256 modified "2023-09-23" @default.
- W2361267256 title "Effect of mifepristone on vascular endothelial function in insulin-resistance rats" @default.
- W2361267256 hasPublicationYear "2009" @default.
- W2361267256 type Work @default.
- W2361267256 sameAs 2361267256 @default.
- W2361267256 citedByCount "0" @default.
- W2361267256 crossrefType "journal-article" @default.
- W2361267256 hasAuthorship W2361267256A5006157399 @default.
- W2361267256 hasConcept C126322002 @default.
- W2361267256 hasConcept C134018914 @default.
- W2361267256 hasConcept C139572402 @default.
- W2361267256 hasConcept C2777391703 @default.
- W2361267256 hasConcept C2777622882 @default.
- W2361267256 hasConcept C2778163477 @default.
- W2361267256 hasConcept C2778826759 @default.
- W2361267256 hasConcept C2779234561 @default.
- W2361267256 hasConcept C2779306644 @default.
- W2361267256 hasConcept C2780972559 @default.
- W2361267256 hasConcept C519581460 @default.
- W2361267256 hasConcept C54355233 @default.
- W2361267256 hasConcept C71924100 @default.
- W2361267256 hasConcept C86803240 @default.
- W2361267256 hasConceptScore W2361267256C126322002 @default.
- W2361267256 hasConceptScore W2361267256C134018914 @default.
- W2361267256 hasConceptScore W2361267256C139572402 @default.
- W2361267256 hasConceptScore W2361267256C2777391703 @default.
- W2361267256 hasConceptScore W2361267256C2777622882 @default.
- W2361267256 hasConceptScore W2361267256C2778163477 @default.
- W2361267256 hasConceptScore W2361267256C2778826759 @default.
- W2361267256 hasConceptScore W2361267256C2779234561 @default.
- W2361267256 hasConceptScore W2361267256C2779306644 @default.
- W2361267256 hasConceptScore W2361267256C2780972559 @default.
- W2361267256 hasConceptScore W2361267256C519581460 @default.
- W2361267256 hasConceptScore W2361267256C54355233 @default.
- W2361267256 hasConceptScore W2361267256C71924100 @default.
- W2361267256 hasConceptScore W2361267256C86803240 @default.
- W2361267256 hasLocation W23612672561 @default.
- W2361267256 hasOpenAccess W2361267256 @default.
- W2361267256 hasPrimaryLocation W23612672561 @default.
- W2361267256 hasRelatedWork W1621816628 @default.
- W2361267256 hasRelatedWork W1764693096 @default.
- W2361267256 hasRelatedWork W1966427108 @default.
- W2361267256 hasRelatedWork W1995731616 @default.
- W2361267256 hasRelatedWork W2033772367 @default.
- W2361267256 hasRelatedWork W2069380359 @default.
- W2361267256 hasRelatedWork W2084522496 @default.
- W2361267256 hasRelatedWork W2095477812 @default.
- W2361267256 hasRelatedWork W2107170420 @default.
- W2361267256 hasRelatedWork W2129639460 @default.
- W2361267256 hasRelatedWork W2161407981 @default.
- W2361267256 hasRelatedWork W2374128428 @default.
- W2361267256 hasRelatedWork W2382953719 @default.
- W2361267256 hasRelatedWork W2408853147 @default.
- W2361267256 hasRelatedWork W2411616013 @default.
- W2361267256 hasRelatedWork W2591687734 @default.
- W2361267256 hasRelatedWork W2610826137 @default.
- W2361267256 hasRelatedWork W2911559519 @default.
- W2361267256 hasRelatedWork W2948255220 @default.
- W2361267256 hasRelatedWork W2965936516 @default.
- W2361267256 isParatext "false" @default.
- W2361267256 isRetracted "false" @default.
- W2361267256 magId "2361267256" @default.
- W2361267256 workType "article" @default.