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- W2361267805 abstract "Objective To investigate the effectiveness and safety of lamivudine and methylprednisolone combined with colquhounia in hepatitis B virus associated glomerulonephritis(HBV-GN)patients.Methods 48cases of HBV-GN were treated by lamivudine and methylprednisolone combined with colquhounia,and the efficacy and adverse reactions of the drugs were evaluated retrospectively.Results The therapy presented effective in 43of 48cases(the total effective rate was 89.6%).Among them,27cases had complete remission,16cases had partial remission,and the remaining 5cases had no reaction.The adverse reactions of the drugs occurred less commonly,including 14cases of light gastrointestinal discomfort,1case of elevated transaminase,1case of high levels of HBV-DNA copies and 1case of a marked WBC falling selectively,and all returned to normal after drug dose adjustment and symptomatic treatment.Conclusion The study indicates that it is effective and safe to treat HBV-GIV patients with lamivudine and methylprednisolone combined with colquhounia.As our study is a small retrospective analysis,it needs a multiple center perspective double-blind RCT study to provide more reliable evidence." @default.
- W2361267805 created "2016-06-24" @default.
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- W2361267805 date "2014-01-01" @default.
- W2361267805 modified "2023-09-23" @default.
- W2361267805 title "Forty-eight cases of HBV-GN treated by lamivudine and methylprednisolone combined with colquhounia" @default.
- W2361267805 hasPublicationYear "2014" @default.
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