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- W2361291272 abstract "Objective:To study the effect of needle implant at Neiguan on expression of VEGF mRNA and protein in myocrardium of the miniswine withmyocardial ischemia injury by gene and protein level,and explor its possible mechanism of anti-ischemic.Methods:32 Guizhou miniswine were randomly divided into four groups including pseudo-operation group,model group,needle implant on Neiguan group,needle implant on Geshu group.Every group have eight miniswine.The animal model of myocardium ischemia was set up by ligation of coronary artery.After needle implant Neiguan,Geshu respectively,mRNA and protein expressions of VEGF by Real time PCR and Western blot methods.Results:Needle implant Neiguan can upregulate the expression of VEGF mRNA and protein,showed obvious difference from modle group(P0.01).Needle implant Geshu showed a tendency to upregulate the expression of VEGF mRNA,but had not obvious difference from the modle group,Geshu and Neiguan both can upregulate the expression of VEGF protein,but had not obvious difference between them.Conclusions:Needle implant Neiguan may protect myocardium tissue through the way of upregulating the mRNA and protein expression of VEGF,increasing capillary density,promoting establishment of collateral circulation,increasing blood flow of ischemic myocardial." @default.
- W2361291272 created "2016-06-24" @default.
- W2361291272 creator A5081281820 @default.
- W2361291272 date "2011-01-01" @default.
- W2361291272 modified "2023-09-25" @default.
- W2361291272 title "Effect of needle implant at Neiguan on expression of VEGF mRNA and protein in myocrardium of the miniswine with myocardial ischemia injury" @default.
- W2361291272 hasPublicationYear "2011" @default.
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