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- W2361332885 abstract "Objective To investigate the influence of general steroidal glycosides from Radix Cynanchi Auriculati combined with cyclophosphamide(CY) on immunity in mice with tumor.Methods The tumor model was established in mice by injection of cell line of liver cancer(H22) and ascites tumor(S180).After drug administration for ten days the mice were weighed and thymus indexes were calculated.The proliferations of T cells and B cells of spleen was detected by MTT.Results When general steroidal glycosides from Radix Cynanchi Auriculati was used alone it had no significant antitumor effect,but increased the thymus indexes compared those with the model group(P0.05) and improved proliferations of T cells and B cells compared with those of model group(P0.001) in mice with tumor.When general steroidal glycosides from Radix Cynanchi Auriculati was combined with CY,it increased significantly the thymus indexes(compared with those of CY group,P0.05) and improved proliferations of T cells and B cells(compared with those of model group,P0.001) in mice with H22 treated with CY.It increased significantly the weight and thymus indexes(compared with those of CY group,P0.05) and improved proliferation of B cells(compared with that of CY group,P0.01) in mice with S180 treated with CY.Conclusion General steroidal glycosides from Radix Cynanchi Auriculati combined with CY can improve cell immunity and humoral immunity in mice after chemotherapy and reduce the toxicity of common chemotherapeutic drugs." @default.
- W2361332885 created "2016-06-24" @default.
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- W2361332885 date "2009-01-01" @default.
- W2361332885 modified "2023-09-23" @default.
- W2361332885 title "Influence of general steroidal glycosides from Radix Cynanchi Auriculati combined with cyclophosphamide on immunity in mice with tumor" @default.
- W2361332885 hasPublicationYear "2009" @default.
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