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- W2361370288 abstract "Objective To explore the effect of Jianpi Xiaozhang Pian on the enterokinesia of mice with depressed gastrointestinal peristalsis induced by atropine.Methods Seventy mice were randomly divided into seven groups:large,medium and small doses of Jianpi Xiaozhang Pian groups,domperidone group,Baohewan group and model group,ten mice in each group.Among the groups,the mice in six groups were made as the model of depressed gastrointestinal peristalsis induced by 0.1 mg·kg-1 atropine through intraperitoneal injection,while in another group as blank control group.Then,the mice in the large,medium and small doses of Jianpi Xiaozhang Pian groups were respectively given with large(180 g·L-1),medium(90 g·L-1) and small(45 g·L-1) doses of Jianpi Xiaozhang Pian suspension by intragastric administration;the mice in domperidone group were given with domperidone suspension;the mice in Baohewan group were given with Baohewan suspension;the mice in model group and blank control group were given with the same volume of sodium carboxymethyl cellulose.All rats were given with carbon powder suspl by intraperitoneal injection after one hour.The rates carbon powder impelling of all groups were calculated,and the incubation period of carbon appeared in feces and the number of feces containing carbon after six hours.Results Compared with the blank control group,the incubation period of carbon appeared in feces in model group was were significantly prolonged(P0.01),the number of feces containing carbon decreased obviously after six hours(P0.01).Compared with the model group,the incubation period of carbon appeared in feces in the large and medium doses of Jianpi Xiaozhang Pian groups,domperidone group and Baohewan group was significantly shorter(P0.01).Compared with the blank control group,the rate of carbon powder impelling in model group were significantly lower(P0.01).Compared with the model group,the rates of carbon powder impelling were significantly higher in the large and medium doses of Jianpi Xiaozhang Pian group,domperidone group and Baohewan group(P0.05).Conclusion Jianpi Xiaozhang Pian can promote the enterokinesia of mice with depressed gastrointestinal peristalsis induced by atropine." @default.
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- W2361370288 date "2012-01-01" @default.
- W2361370288 modified "2023-09-23" @default.
- W2361370288 title "Effect of Jianpi Xiaozhang Pian on the enterokinesia of the mice with depressed gastrointestinal peristalsis induced by atropine" @default.
- W2361370288 hasPublicationYear "2012" @default.
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