Matches in SemOpenAlex for { <https://semopenalex.org/work/W2361384229> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2361384229 abstract "Objective To investigate the relationship between insulin receptor tyrosine kinase(IRTK) of the skeletal muscle and insulin resistance of the women with gestational diabetes mellitus(GDM). Methods The activity of IRTK of skeletal muscle was determined by ELISA in 30 patients with GDM(GDM group),30 normal pregnant women(normal-pregnancy group) and 20 non-pregnant women(control group).Fasting plasma glucose(FPG) and fasting insulin(FINS) were measured by oxidized assay and immunoradioassay.Insulin resistant index(HOMA-IR) was calculated according to the data of FPG and FINS.Results The levels of FPG,FINS and HOMA-IR of the GDM group were significantly higher than that of the normal-pregnancy group(F=21.7-40.2,q=5.42-10.56,P0.01).The levels of FINS and HOMA-IR of the normal pregnancy group were significantly higher than that of the control group(q=3.76,4.36;P0.01).Before insulin stimulation,no significant differences were found among the three groups in terms of the IRTK activities(P0.05);After insulin stimulation,the IRTK activities increased in all the subjects,but the IRTK activities of the GDM group were significantly lower than that of the normal-pregnancy group(F=95.0,q=10.95,P0.01);while that of the normal-pregnant group was lower than that of the control(q=9.52,P0.01).HOMA-IR of the GDM group was negatively correlated with the IRTK activity after insulin stimulation(r=-0.625,P0.01). Conclusion Decreased insulin receptor tyrosine kinase of the skeletal muscle may be one of the molecular mechanisms of the insulin resistance in women with GDM." @default.
- W2361384229 created "2016-06-24" @default.
- W2361384229 creator A5038511943 @default.
- W2361384229 date "2011-01-01" @default.
- W2361384229 modified "2023-09-27" @default.
- W2361384229 title "RELATIONSHIP BETWEEN INSULIN RECEPTOR TYROSINE KINASE OF THE SKELETAL MUSCLE AND INSULIN RESISTANCE OF WOMEN WITH GESTATIONAL DIABETES MELLITUS" @default.
- W2361384229 hasPublicationYear "2011" @default.
- W2361384229 type Work @default.
- W2361384229 sameAs 2361384229 @default.
- W2361384229 citedByCount "0" @default.
- W2361384229 crossrefType "journal-article" @default.
- W2361384229 hasAuthorship W2361384229A5038511943 @default.
- W2361384229 hasConcept C112446052 @default.
- W2361384229 hasConcept C126322002 @default.
- W2361384229 hasConcept C134018914 @default.
- W2361384229 hasConcept C170493617 @default.
- W2361384229 hasConcept C2777391703 @default.
- W2361384229 hasConcept C2779234561 @default.
- W2361384229 hasConcept C2779306644 @default.
- W2361384229 hasConcept C2779434492 @default.
- W2361384229 hasConcept C2779959927 @default.
- W2361384229 hasConcept C42362537 @default.
- W2361384229 hasConcept C46973012 @default.
- W2361384229 hasConcept C54355233 @default.
- W2361384229 hasConcept C555293320 @default.
- W2361384229 hasConcept C71924100 @default.
- W2361384229 hasConcept C86803240 @default.
- W2361384229 hasConceptScore W2361384229C112446052 @default.
- W2361384229 hasConceptScore W2361384229C126322002 @default.
- W2361384229 hasConceptScore W2361384229C134018914 @default.
- W2361384229 hasConceptScore W2361384229C170493617 @default.
- W2361384229 hasConceptScore W2361384229C2777391703 @default.
- W2361384229 hasConceptScore W2361384229C2779234561 @default.
- W2361384229 hasConceptScore W2361384229C2779306644 @default.
- W2361384229 hasConceptScore W2361384229C2779434492 @default.
- W2361384229 hasConceptScore W2361384229C2779959927 @default.
- W2361384229 hasConceptScore W2361384229C42362537 @default.
- W2361384229 hasConceptScore W2361384229C46973012 @default.
- W2361384229 hasConceptScore W2361384229C54355233 @default.
- W2361384229 hasConceptScore W2361384229C555293320 @default.
- W2361384229 hasConceptScore W2361384229C71924100 @default.
- W2361384229 hasConceptScore W2361384229C86803240 @default.
- W2361384229 hasOpenAccess W2361384229 @default.
- W2361384229 hasRelatedWork W1978667553 @default.
- W2361384229 hasRelatedWork W2258092295 @default.
- W2361384229 hasRelatedWork W2314596775 @default.
- W2361384229 hasRelatedWork W2348306765 @default.
- W2361384229 hasRelatedWork W2354853433 @default.
- W2361384229 hasRelatedWork W2363019970 @default.
- W2361384229 hasRelatedWork W2363167695 @default.
- W2361384229 hasRelatedWork W2373130407 @default.
- W2361384229 hasRelatedWork W2376093029 @default.
- W2361384229 hasRelatedWork W2380434003 @default.
- W2361384229 hasRelatedWork W2385503151 @default.
- W2361384229 hasRelatedWork W2387463803 @default.
- W2361384229 hasRelatedWork W3005342559 @default.
- W2361384229 hasRelatedWork W3029817325 @default.
- W2361384229 hasRelatedWork W3029846143 @default.
- W2361384229 hasRelatedWork W3031011838 @default.
- W2361384229 hasRelatedWork W3032040088 @default.
- W2361384229 hasRelatedWork W3032283266 @default.
- W2361384229 hasRelatedWork W3032568611 @default.
- W2361384229 hasRelatedWork W3044620544 @default.
- W2361384229 isParatext "false" @default.
- W2361384229 isRetracted "false" @default.
- W2361384229 magId "2361384229" @default.
- W2361384229 workType "article" @default.